Search results for "Medical Laboratory Science"

showing 3 items of 3 documents

Infrared microspectroscopic determination of collagen cross-links in articular cartilage

2017

Collagen forms an organized network in articular cartilage to give tensile stiffness to the tissue. Due to its long half-life, collagen is susceptible to cross-links caused by advanced glycation end-products. The current standard method for determination of cross-link concentrations in tissues is the destructive high-performance liquid chromatography (HPLC). The aim of this study was to analyze the cross-link concentrations nondestructively from standard unstained histological articular cartilage sections by using Fourier transform infrared (FTIR) microspectroscopy. Half of the bovine articular cartilage samples ( n = 27 ) were treated with threose to increase the collagen cross-linking whi…

0301 basic medicineCartilage ArticularGlycation End Products AdvancedcollagenSpectrophotometry InfraredPROTEOGLYCAN01 natural sciencesHigh-performance liquid chromatographychemistry.chemical_compoundBiomedicinsk laboratorievetenskap/teknologiPartial least squares regressionBiomedical Laboratory Science/Technologyinfrared spectroscopyPyridinolineThreoseChemistryMedicinsk bildbehandlingSTIFFNESSinfrapunaspektroskopiata3141AnatomyAtomic and Molecular Physics and OpticsDIFFUSIONElectronic Optical and Magnetic Materialsmedicine.anatomical_structuremultivariate analysisGLYCATION END-PRODUCTSNONENZYMATIC GLYCATIONBiomedical EngineeringInfrared spectroscopyI COLLAGENFORMALIN FIXATIONcross-linksOrthopaedicsBiomaterials03 medical and health sciencesmedicineAnimalsarticular cartilageFourier transform infrared spectroscopyPentosidineLeast-Squares Analysista217ChromatographyCartilage010401 analytical chemistry3126 Surgery anesthesiology intensive care radiology0104 chemical sciencesMedical Image Processing030104 developmental biologyOrtopedi1182 Biochemistry cell and molecular biologyCattleJournal of Biomedical Optics
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Current trends in biocompatibility testing

1998

Biocompatibility remains the central theme for biomaterials applications in medicine. It is generally accepted that this term means not only absence of a cytotoxic effect but also positive effects in the sense of biofunctionality, i.e. promotion of biological processes which further the intended aim of the application of a biomaterial. The national and international standards for testing regimes represent a lowest common denominator for such applications and do not necessarily ensure that optimal function will be achieved. The authors' thesis is that biocompatibility testing has scope for extensive development with respect to biofunctionality. The present paper reviews current trends in the…

In Vitro TechniquesBiocompatibilitymedia_common.quotation_subjectCytological TechniquesBiocompatible MaterialsNanotechnologyIn Vitro TechniquesBiologyOrgan development03 medical and health sciences0302 clinical medicineMaterials TestingCell AdhesionMedical Laboratory ScienceAnimalsHumansLowest common denominatorFunction (engineering)Cells Culturedmedia_commonScope (project management)Mechanical EngineeringBiocompatibility TestingReproducibility of ResultsGeneral MedicineCytotoxicity Tests ImmunologicCritical appraisalRisk analysis (engineering)030220 oncology & carcinogenesisStress MechanicalRheology030217 neurology & neurosurgeryForecastingProceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine
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Laboratory medicine and sports : between Scylla and Charybdis

2012

Laboratory medicine is complex and contributes to the diagnosis, therapeutic monitoring and follow-up of acquired and inherited human disorders. The regular practice of physical exercise provides important benefits in heath and disease and sports medicine is thereby receiving growing focus from almost each and every clinical discipline, including laboratory medicine. Sport-laboratory medicine is a relatively innovative branch of laboratory science, which can provide valuable contributions to the diagnosis and follow-up of athletic injuries, and which is acquiring a growing clinical significance to support biomechanics and identify novel genomics and "exercisenomics" patterns that can help i…

medicine.medical_specialtySports medicineCheatingClinical BiochemistryAlternative medicineMEDLINEMedical laboratoryphysical activitydopingantidopingSports MedicinemedicineMilestone (project management)Medical Laboratory ScienceDopingHumansExerciseDoping in SportsMedical educationbiologybusiness.industryOvertrainingAthletesPhysical activityBiochemistry (medical)General Medicinemedicine.diseasebiology.organism_classificationSports medicinePhysical therapyantidoping; doping; exercise; physical activity; sports medicinebusinessAntidopinghuman activitiesSports
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